What is chemical genomics
Chemical genomics is a field that integrates chemistry and genomics to explore the genetic basis of disease through the use of small molecules. These small molecules can be used to modulate gene function in a rapid, reversible, and dose-dependent manner, offering a powerful approach to study gene function, signal transduction pathways, and cellular processes in a high-throughput manner. This technique not only aids in identifying the molecular mechanisms of diseases but also facilitates the discovery and development of new drugs by targeting specific genetic pathways.[1]
Reference
[1]Markossian, S., Ang, K. K., Wilson, C. G., & Arkin, M. R. (2018). Small-molecule screening for genetic diseases. Annual review of genomics and human genetics, 19, 263-288.
[1]Markossian, S., Ang, K. K., Wilson, C. G., & Arkin, M. R. (2018). Small-molecule screening for genetic diseases. Annual review of genomics and human genetics, 19, 263-288.